First inappropriate implantable cardioverter defibrillator therapy is often due to inaccurate device programming: analysis of the French OPERA registry.
Identifieur interne : 000704 ( Main/Exploration ); précédent : 000703; suivant : 000705First inappropriate implantable cardioverter defibrillator therapy is often due to inaccurate device programming: analysis of the French OPERA registry.
Auteurs : Antoine Leenhardt [France] ; Pascal Defaye [France] ; Elisabeth Mouton ; Marc Delay ; Nicolas Delarche ; Jean-Marc Dupuis ; Olivier Bizeau ; Philippe Mabo [France] ; Saida Cheggour ; Dominique BabutySource :
- EP-Europace [ 1099-5129 ] ; 2012-10.
English descriptors
- mix :
Abstract
AIMS: Inappropriate therapy delivered by implantable cardioverter defibrillators (ICDs) remains a challenge. The OPERA registry measured the times to, and studied the determinants of, first appropriate (FAT) and inappropriate (FIT) therapies delivered by single-, dual- and triple-chamber [cardiac resynchronization therapy defibrillator (CRT-D)] ICD. METHODS AND RESULTS: We entered 636 patients (mean age = 62.0 ± 13.5 years; 88% men) in the registry, of whom 251 received single-, 238 dual-, and 147 triple-chamber ICD, for primary (30.5%) or secondary (69.5%) indications. We measured times to FAT and FIT as a function of multiple clinical characteristics, examined the effects of various algorithm components on the likelihood of FAT and FIT delivery, and searched for predictors of FAT and FIT. Over 22.8 ± 8.8 months of observation, 184 patients (28.9%) received FAT and 70 (11.0%) received FIT. Ventricular tachycardia (VT) was the trigger of 88% of FAT, and supraventricular tachycardia was the trigger of 91% of FIT. The median times to FIT (90 days; range 49-258) and FAT (171 days; 50-363) were similar. The rate of FAT was higher (P <0.001) in patients treated for secondary than primary indications, while that of FIT were similar in both groups. Out of 57 analysable FIT, 27 (47.4%) could have been prevented by fine tuning the device programming like the sustained rate duration or the VT discrimination algorithm. CONCLUSIONS: First inappropriate therapy occurred in 11% of 636 ICD recipients followed for ∼2 years. Nearly 50% of FIT could have been prevented by improving device programming.
Url:
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream Hal, to step Corpus: 000086
- to stream Hal, to step Curation: 000086
- to stream Hal, to step Checkpoint: 000205
- to stream Main, to step Merge: 000705
- to stream Main, to step Curation: 000704
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">First inappropriate implantable cardioverter defibrillator therapy is often due to inaccurate device programming: analysis of the French OPERA registry.</title><author><name sortKey="Leenhardt, Antoine" sort="Leenhardt, Antoine" uniqKey="Leenhardt A" first="Antoine" last="Leenhardt">Antoine Leenhardt</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-209011" status="INCOMING"><orgName>Service de Cardiologie</orgName><desc><address><addrLine>46 Rue Henri Huchard 75018 Paris</addrLine><country key="FR"></country></address></desc><listRelation><relation active="#struct-300156" type="direct"></relation><relation active="#struct-300301" type="direct"></relation><relation active="#struct-302037" type="direct"></relation><relation active="#struct-351120" type="direct"></relation></listRelation><tutelles><tutelle active="#struct-300156" type="direct"><org type="institution" xml:id="struct-300156" status="VALID"><orgName>Hôpital Bichat - Claude Bernard</orgName><desc><address><country key="FR"></country></address></desc></org></tutelle><tutelle active="#struct-300301" type="direct"><org type="institution" xml:id="struct-300301" status="VALID"><orgName>Université Paris Diderot - Paris 7</orgName><orgName type="acronym">UP7</orgName><desc><address><addrLine>5 rue Thomas-Mann - 75205 Paris cedex 13</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-paris-diderot.fr</ref></desc></org></tutelle><tutelle active="#struct-302037" type="direct"><org type="institution" xml:id="struct-302037" status="OLD"><orgName>PRES Sorbonne Paris Cité</orgName><desc><address><country key="FR"></country></address></desc></org></tutelle><tutelle active="#struct-351120" type="direct"><org type="institution" xml:id="struct-351120" status="INCOMING"><orgName>Centre de Référence Maladies Cardiaques Héréditaires</orgName><desc><address><country key="FR"></country></address></desc></org></tutelle></tutelles></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Defaye, Pascal" sort="Defaye, Pascal" uniqKey="Defaye P" first="Pascal" last="Defaye">Pascal Defaye</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-94817" status="INCOMING"><orgName>Cardiac Stimulation and Rhythmology</orgName><desc><address><addrLine>Cardiology Department</addrLine><country key="FR"></country></address></desc><listRelation><relation active="#struct-300071" type="direct"></relation></listRelation><tutelles><tutelle active="#struct-300071" type="direct"><org type="institution" xml:id="struct-300071" status="VALID"><orgName>CHU Grenoble</orgName><desc><address><country key="FR"></country></address></desc></org></tutelle></tutelles></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Mouton, Elisabeth" sort="Mouton, Elisabeth" uniqKey="Mouton E" first="Elisabeth" last="Mouton">Elisabeth Mouton</name></author><author><name sortKey="Delay, Marc" sort="Delay, Marc" uniqKey="Delay M" first="Marc" last="Delay">Marc Delay</name></author><author><name sortKey="Delarche, Nicolas" sort="Delarche, Nicolas" uniqKey="Delarche N" first="Nicolas" last="Delarche">Nicolas Delarche</name></author><author><name sortKey="Dupuis, Jean Marc" sort="Dupuis, Jean Marc" uniqKey="Dupuis J" first="Jean-Marc" last="Dupuis">Jean-Marc Dupuis</name></author><author><name sortKey="Bizeau, Olivier" sort="Bizeau, Olivier" uniqKey="Bizeau O" first="Olivier" last="Bizeau">Olivier Bizeau</name></author><author><name sortKey="Mabo, Philippe" sort="Mabo, Philippe" uniqKey="Mabo P" first="Philippe" last="Mabo">Philippe Mabo</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-29417" status="VALID"><orgName>Service de cardiologie et maladies vasculaires</orgName><desc><address><addrLine>2 rue Henri Le Guilloux 35033 Rennes cedex 9</addrLine><country key="FR"></country></address><ref type="url">http://www.chu-rennes.fr/</ref></desc><listRelation><relation active="#struct-105160" type="direct"></relation><relation active="#struct-300129" type="direct"></relation><relation active="#struct-301327" type="direct"></relation></listRelation><tutelles><tutelle active="#struct-105160" type="direct"><org type="institution" xml:id="struct-105160" status="VALID"><orgName>Université de Rennes 1</orgName><orgName type="acronym">UR1</orgName><desc><address><addrLine>2 rue du Thabor - CS 46510 - 35065 Rennes cedex</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-rennes1.fr/</ref></desc></org></tutelle><tutelle active="#struct-300129" type="direct"><org type="institution" xml:id="struct-300129" status="VALID"><orgName>Hôpital Pontchaillou</orgName><desc><address><country key="FR"></country></address></desc></org></tutelle><tutelle active="#struct-301327" type="direct"><org type="institution" xml:id="struct-301327" status="VALID"><orgName>Centre hospitalier universitaire [Rennes]</orgName><orgName type="acronym">CHU</orgName><desc><address><addrLine>2 Rue Henri le Guilloux, 35000 Rennes</addrLine><country key="FR"></country></address><ref type="url">http://www.chu-rennes.fr/</ref></desc></org></tutelle></tutelles></hal:affiliation><country>France</country><placeName><settlement type="city">Rennes</settlement><region type="region" nuts="2">Région Bretagne</region></placeName><orgName type="university">Université de Rennes 1</orgName><orgName type="institution" wicri:auto="newGroup">Université européenne de Bretagne</orgName></affiliation></author><author><name sortKey="Cheggour, Saida" sort="Cheggour, Saida" uniqKey="Cheggour S" first="Saida" last="Cheggour">Saida Cheggour</name></author><author><name sortKey="Babuty, Dominique" sort="Babuty, Dominique" uniqKey="Babuty D" first="Dominique" last="Babuty">Dominique Babuty</name></author></titleStmt><publicationStmt><idno type="wicri:source">HAL</idno><idno type="RBID">Hal:hal-00904932</idno><idno type="halId">hal-00904932</idno><idno type="halUri">https://hal.archives-ouvertes.fr/hal-00904932</idno><idno type="url">https://hal.archives-ouvertes.fr/hal-00904932</idno><date when="2012-10">2012-10</date><idno type="wicri:Area/Hal/Corpus">000086</idno><idno type="wicri:Area/Hal/Curation">000086</idno><idno type="wicri:Area/Hal/Checkpoint">000205</idno><idno type="wicri:doubleKey">1099-5129:2012:Leenhardt A:first:inappropriate:implantable</idno><idno type="wicri:Area/Main/Merge">000705</idno><idno type="wicri:Area/Main/Curation">000704</idno><idno type="wicri:Area/Main/Exploration">000704</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">First inappropriate implantable cardioverter defibrillator therapy is often due to inaccurate device programming: analysis of the French OPERA registry.</title><author><name sortKey="Leenhardt, Antoine" sort="Leenhardt, Antoine" uniqKey="Leenhardt A" first="Antoine" last="Leenhardt">Antoine Leenhardt</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-209011" status="INCOMING"><orgName>Service de Cardiologie</orgName><desc><address><addrLine>46 Rue Henri Huchard 75018 Paris</addrLine><country key="FR"></country></address></desc><listRelation><relation active="#struct-300156" type="direct"></relation><relation active="#struct-300301" type="direct"></relation><relation active="#struct-302037" type="direct"></relation><relation active="#struct-351120" type="direct"></relation></listRelation><tutelles><tutelle active="#struct-300156" type="direct"><org type="institution" xml:id="struct-300156" status="VALID"><orgName>Hôpital Bichat - Claude Bernard</orgName><desc><address><country key="FR"></country></address></desc></org></tutelle><tutelle active="#struct-300301" type="direct"><org type="institution" xml:id="struct-300301" status="VALID"><orgName>Université Paris Diderot - Paris 7</orgName><orgName type="acronym">UP7</orgName><desc><address><addrLine>5 rue Thomas-Mann - 75205 Paris cedex 13</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-paris-diderot.fr</ref></desc></org></tutelle><tutelle active="#struct-302037" type="direct"><org type="institution" xml:id="struct-302037" status="OLD"><orgName>PRES Sorbonne Paris Cité</orgName><desc><address><country key="FR"></country></address></desc></org></tutelle><tutelle active="#struct-351120" type="direct"><org type="institution" xml:id="struct-351120" status="INCOMING"><orgName>Centre de Référence Maladies Cardiaques Héréditaires</orgName><desc><address><country key="FR"></country></address></desc></org></tutelle></tutelles></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Defaye, Pascal" sort="Defaye, Pascal" uniqKey="Defaye P" first="Pascal" last="Defaye">Pascal Defaye</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-94817" status="INCOMING"><orgName>Cardiac Stimulation and Rhythmology</orgName><desc><address><addrLine>Cardiology Department</addrLine><country key="FR"></country></address></desc><listRelation><relation active="#struct-300071" type="direct"></relation></listRelation><tutelles><tutelle active="#struct-300071" type="direct"><org type="institution" xml:id="struct-300071" status="VALID"><orgName>CHU Grenoble</orgName><desc><address><country key="FR"></country></address></desc></org></tutelle></tutelles></hal:affiliation><country>France</country></affiliation></author><author><name sortKey="Mouton, Elisabeth" sort="Mouton, Elisabeth" uniqKey="Mouton E" first="Elisabeth" last="Mouton">Elisabeth Mouton</name></author><author><name sortKey="Delay, Marc" sort="Delay, Marc" uniqKey="Delay M" first="Marc" last="Delay">Marc Delay</name></author><author><name sortKey="Delarche, Nicolas" sort="Delarche, Nicolas" uniqKey="Delarche N" first="Nicolas" last="Delarche">Nicolas Delarche</name></author><author><name sortKey="Dupuis, Jean Marc" sort="Dupuis, Jean Marc" uniqKey="Dupuis J" first="Jean-Marc" last="Dupuis">Jean-Marc Dupuis</name></author><author><name sortKey="Bizeau, Olivier" sort="Bizeau, Olivier" uniqKey="Bizeau O" first="Olivier" last="Bizeau">Olivier Bizeau</name></author><author><name sortKey="Mabo, Philippe" sort="Mabo, Philippe" uniqKey="Mabo P" first="Philippe" last="Mabo">Philippe Mabo</name><affiliation wicri:level="1"><hal:affiliation type="laboratory" xml:id="struct-29417" status="VALID"><orgName>Service de cardiologie et maladies vasculaires</orgName><desc><address><addrLine>2 rue Henri Le Guilloux 35033 Rennes cedex 9</addrLine><country key="FR"></country></address><ref type="url">http://www.chu-rennes.fr/</ref></desc><listRelation><relation active="#struct-105160" type="direct"></relation><relation active="#struct-300129" type="direct"></relation><relation active="#struct-301327" type="direct"></relation></listRelation><tutelles><tutelle active="#struct-105160" type="direct"><org type="institution" xml:id="struct-105160" status="VALID"><orgName>Université de Rennes 1</orgName><orgName type="acronym">UR1</orgName><desc><address><addrLine>2 rue du Thabor - CS 46510 - 35065 Rennes cedex</addrLine><country key="FR"></country></address><ref type="url">http://www.univ-rennes1.fr/</ref></desc></org></tutelle><tutelle active="#struct-300129" type="direct"><org type="institution" xml:id="struct-300129" status="VALID"><orgName>Hôpital Pontchaillou</orgName><desc><address><country key="FR"></country></address></desc></org></tutelle><tutelle active="#struct-301327" type="direct"><org type="institution" xml:id="struct-301327" status="VALID"><orgName>Centre hospitalier universitaire [Rennes]</orgName><orgName type="acronym">CHU</orgName><desc><address><addrLine>2 Rue Henri le Guilloux, 35000 Rennes</addrLine><country key="FR"></country></address><ref type="url">http://www.chu-rennes.fr/</ref></desc></org></tutelle></tutelles></hal:affiliation><country>France</country><placeName><settlement type="city">Rennes</settlement><region type="region" nuts="2">Région Bretagne</region></placeName><orgName type="university">Université de Rennes 1</orgName><orgName type="institution" wicri:auto="newGroup">Université européenne de Bretagne</orgName></affiliation></author><author><name sortKey="Cheggour, Saida" sort="Cheggour, Saida" uniqKey="Cheggour S" first="Saida" last="Cheggour">Saida Cheggour</name></author><author><name sortKey="Babuty, Dominique" sort="Babuty, Dominique" uniqKey="Babuty D" first="Dominique" last="Babuty">Dominique Babuty</name></author></analytic><series><title level="j">EP-Europace</title><idno type="ISSN">1099-5129</idno><imprint><date type="datePub">2012-10</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="mix" xml:lang="en"><term>Atrial fibrillation</term><term>Implantable cardioverter defibrillator</term><term>Inappropriate therapy</term><term>Supraventricular tachyarrhythmia</term><term>Ventricular tachyarrhythmia</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">AIMS: Inappropriate therapy delivered by implantable cardioverter defibrillators (ICDs) remains a challenge. The OPERA registry measured the times to, and studied the determinants of, first appropriate (FAT) and inappropriate (FIT) therapies delivered by single-, dual- and triple-chamber [cardiac resynchronization therapy defibrillator (CRT-D)] ICD. METHODS AND RESULTS: We entered 636 patients (mean age = 62.0 ± 13.5 years; 88% men) in the registry, of whom 251 received single-, 238 dual-, and 147 triple-chamber ICD, for primary (30.5%) or secondary (69.5%) indications. We measured times to FAT and FIT as a function of multiple clinical characteristics, examined the effects of various algorithm components on the likelihood of FAT and FIT delivery, and searched for predictors of FAT and FIT. Over 22.8 ± 8.8 months of observation, 184 patients (28.9%) received FAT and 70 (11.0%) received FIT. Ventricular tachycardia (VT) was the trigger of 88% of FAT, and supraventricular tachycardia was the trigger of 91% of FIT. The median times to FIT (90 days; range 49-258) and FAT (171 days; 50-363) were similar. The rate of FAT was higher (P <0.001) in patients treated for secondary than primary indications, while that of FIT were similar in both groups. Out of 57 analysable FIT, 27 (47.4%) could have been prevented by fine tuning the device programming like the sustained rate duration or the VT discrimination algorithm. CONCLUSIONS: First inappropriate therapy occurred in 11% of 636 ICD recipients followed for ∼2 years. Nearly 50% of FIT could have been prevented by improving device programming.</div></front></TEI><affiliations><list><country><li>France</li></country><region><li>Région Bretagne</li></region><settlement><li>Rennes</li></settlement><orgName><li>Université de Rennes 1</li><li>Université européenne de Bretagne</li></orgName></list><tree><noCountry><name sortKey="Babuty, Dominique" sort="Babuty, Dominique" uniqKey="Babuty D" first="Dominique" last="Babuty">Dominique Babuty</name><name sortKey="Bizeau, Olivier" sort="Bizeau, Olivier" uniqKey="Bizeau O" first="Olivier" last="Bizeau">Olivier Bizeau</name><name sortKey="Cheggour, Saida" sort="Cheggour, Saida" uniqKey="Cheggour S" first="Saida" last="Cheggour">Saida Cheggour</name><name sortKey="Delarche, Nicolas" sort="Delarche, Nicolas" uniqKey="Delarche N" first="Nicolas" last="Delarche">Nicolas Delarche</name><name sortKey="Delay, Marc" sort="Delay, Marc" uniqKey="Delay M" first="Marc" last="Delay">Marc Delay</name><name sortKey="Dupuis, Jean Marc" sort="Dupuis, Jean Marc" uniqKey="Dupuis J" first="Jean-Marc" last="Dupuis">Jean-Marc Dupuis</name><name sortKey="Mouton, Elisabeth" sort="Mouton, Elisabeth" uniqKey="Mouton E" first="Elisabeth" last="Mouton">Elisabeth Mouton</name></noCountry><country name="France"><noRegion><name sortKey="Leenhardt, Antoine" sort="Leenhardt, Antoine" uniqKey="Leenhardt A" first="Antoine" last="Leenhardt">Antoine Leenhardt</name></noRegion><name sortKey="Defaye, Pascal" sort="Defaye, Pascal" uniqKey="Defaye P" first="Pascal" last="Defaye">Pascal Defaye</name><name sortKey="Mabo, Philippe" sort="Mabo, Philippe" uniqKey="Mabo P" first="Philippe" last="Mabo">Philippe Mabo</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Musique/explor/OperaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 000704 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 000704 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Musique
|area= OperaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= Hal:hal-00904932
|texte= First inappropriate implantable cardioverter defibrillator therapy is often due to inaccurate device programming: analysis of the French OPERA registry.
}}
| This area was generated with Dilib version V0.6.21. |  |